219325-61-8Relevant articles and documents
Indolequinone antitumor agents: Correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity
Beall, Howard D.,Winski, Shannon,Swann, Elizabeth,Hudnott, Anna R.,Cotterill, Ann S.,O'Sullivan, Noeleen,Green, Stephen J.,Bien, Richard,Siegel, David,Ross, David,Moody, Christopher J.
, p. 4755 - 4766 (2007/10/03)
A series of indolequinones bearing various functional groups has been synthesized, and the effects of substituents on the metabolism of the quinones by recombinant human NAD(P)H: quinone oxidoreductase (NQO1) were studied. Thus 5-methoxyindolequinones wer