219491-92-6

Basic information

• Product Name: Benzamide, 2-amino-N-(4-methoxyphenyl)-4-nitro-
• CAS NO: 219491-92-6
• Molecular Formula: C14H13N3O4
• Molecular Weight: 287.275
• Mol File: 219491-92-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-amino-N-(4-methoxyphenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-amino-N-(4-methoxyphenyl)-4-nitro-(219491-92-6)
• EPA Substance Registry System: Benzamide, 2-amino-N-(4-methoxyphenyl)-4-nitro-(219491-92-6)

Safety Data

• Hazardous Substances Data: 219491-92-6(Hazardous Substances Data)

Upstream product

• 619-17-0 4-Nitroanthranilic acid 
• 63480-10-4 4-nitroisatoic anhydride 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 219493-03-5 4-Amino-2-(4-tert-butyl-benzoylamino)-N-(4-methoxy-phenyl)-benzamide 
• 263558-92-5 4-Amino-2-(4-dimethylamino-benzoylamino)-N-(4-methoxy-phenyl)-benzamide 
• 219491-93-7 2-(4-tert-butylbenzoylamino)-4-nitro-N-(4-methoxyphenyl)benzamide 
• 263559-03-1 2-[4-(dimethylamino)benzoylamino]-N-(4-methoxyphenyl)-4-nitrobenzamide 

Relevant articles and documents

N2-aroylanthranilamide inhibitors of human factor Xa

Reversal of the A-ring amide link in 1,2-dibenzamidobenzene 1 (fXa K(ass) = 0.81 x 106 L/mol) led to a series of human factor Xa (hfXa) inhibitors based on N2-aroylanthranilamide 4. Expansion of the SAR around 4 showed that only smal

Antithrombotic agents

This application relates to a compound of formula (I), a pharmaceutically acceptable salt of the compound, or a prodrug thereof, as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa, as well as a process for its preparation and intermediates therefor.