Cas 219502-13-3,(E)-3-(4-Allyloxy-phenyl)-acryloyl chloride

219502-13-3

Post Buying Request

Basic information

Product Name: (E)-3-(4-Allyloxy-phenyl)-acryloyl chloride
Synonyms: (E)-3-(4-Allyloxy-phenyl)-acryloyl chloride
CAS NO:219502-13-3
Molecular Formula:
Molecular Weight: 222.671
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (E)-3-(4-Allyloxy-phenyl)-acryloyl chloride(CAS DataBase Reference)
NIST Chemistry Reference: (E)-3-(4-Allyloxy-phenyl)-acryloyl chloride(219502-13-3)
EPA Substance Registry System: (E)-3-(4-Allyloxy-phenyl)-acryloyl chloride(219502-13-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 219502-13-3(Hazardous Substances Data)

Suppliers
Usage
Upstream product
Downstream Products
Article

219502-13-3 Suppliers

Recommended suppliers

219502-13-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 219502-13-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,5,0 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 219502-13:
(8*2)+(7*1)+(6*9)+(5*5)+(4*0)+(3*2)+(2*1)+(1*3)=113
113 % 10 = 3
So 219502-13-3 is a valid CAS Registry Number.

219502-13-3Upstream product

219502-13-3Downstream Products

219502-13-3Relevant academic research and scientific papers

Synthesis, cytotoxicity and molecular modelling studies of new phenylcinnamide derivatives as potent inhibitors of cholinesterases

Saeed, Aamer,Mahesar, Parvez Ali,Zaib, Sumera,Khan, Muhammad Siraj,Matin, Abdul,Shahid, Mohammad,Iqbal, Jamshed

, p. 43 - 53 (2014/04/17)

The present study reports the synthesis of cinnamide derivatives and their biological activity as inhibitors of both cholinesterases and anticancer agents. Controlled inhibition of brain acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) may slow neurodegeneration in Alzheimer's diseases (AD). The anticholinesterase activity of phenylcinnamide derivatives was determined against Electric Eel acetylcholinesterase (EeAChE) and horse serum butyrylcholinesterase (hBChE) and some of the compounds appeared as moderately potent inhibitors of EeAChE and hBChE. The compound 3-(2-(Benzyloxy)phenyl)-N- (3,4,5-trimethoxyphenyl)acrylamide (3i) showed maximum activity against EeAChE with an IC50 0.29 ± 0.21 μM whereas 3-(2-chloro-6- nitrophenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide (3k) was proved to be the most potent inhibitor of hBChE having IC50 1.18 ± 1.31 μM. To better understand the enzyme-inhibitor interaction of the most active compounds toward cholinesterases, molecular modelling studies were carried out on high-resolution crystallographic structures. The anticancer effects of synthesized compounds were also evaluated against cancer cell line (lung carcinoma). The compounds may be useful leads for the design of a new class of anticancer drugs for the treatment of cancer and cholinesterase inhibitors for Alzheimer's disease (AD).

Studies of hypolipidemic agents. 1. Synthesis and hypolipidemic activities of alkoxycinnamic acid derivatives

Watanabe,Hayashi,Yoshimatsu,Sakai,Takeyama,Takashima

, p. 50 - 59 (2007/10/02)

More than 110 derivatives of alkoxycinnamic acids were synthesized and their hypolipidemic activities were evaluated in a screening system with rats. Cinnamic acids, α-methylcinnamic acids, and their various esters with a higher p-alkoxy substituent were

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 219502-13-3