219558-46-0Relevant academic research and scientific papers
Conformationally constrained no synthase inhibitors: Rigid analogs of L- N-iminoethylornithine
Eustache, Jacques,Grob, Alfred,Lam, Charles,Sellier, Odile,Schulz, Gerhard
, p. 2961 - 2966 (2007/10/03)
The synthesis of eight rigid analogs of L-N-iminoethylomithine (L-NIO) is described. The compounds have been evaluated for their inhibition of inducible nitric oxide synthase. Preliminary structure-activity relationships are discussed.
