219573-46-3

Upstream product

• 280583-57-5 1-(2-chloro-4-iodobenzyl)-6-(ethoxycarbonyl)-2-methylbenzimidazole 
• 859080-50-5 2-thiophenylboric acid 

Downstream Products

• 219573-48-5 6-carboxy-1-(2-chloro-4-(thiophen-2-yl)benzyl)-2-methylbenzimidazole> 
• 219573-50-9 6-carboxy-1-(2-chloro-4-(2-furyl)benzyl)-2-methylbenzimidazole> 

Relevant academic research and scientific papers

Benzimidazole derivatives

A novel benzimidazole derivative or a salt thereof is provided, which is represented by the formula: wherein R1represents an alkyl group, etc., R2represents a substituted or unsubstituted aromatic lower alkyl group, R3represents an alkyl group, etc., and -X- is represented by the following formula (V): etc. This derivative or a salt thereof is useful as medicine.

BENZIMIDAZOLE DERIVATIVES

The present invention provides novel benzimidazole derivatives of the following formula (I) and salts thereof: wherein R1 represents a lower alkyl group or a lower alkyloxy-lower alkyl group: R2 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 8 carbon atoms, an aryl group, and such; R3 represents a lower alkyl group, a lower alkenyl group, an aryl group, a lower alkylaryl group, an aryl-lower alkenyl group, a halothienyl group, a lower alkylamino group, or an aryl-lower alkylamino group; A represents a benzene ring, a naphthalene ring, or a pyridine ring; and X represents a halogen atom. The derivatives and their salts have blood sugar level-depressing activity or PDE5-inhibiting activity, and are useful as pharmaceutical preparations.