219585-99-6

Upstream product

• 501-53-1 benzyl chloroformate 
• 145452-11-5 (S)-2-Amino-2-isobutyl-5-methyl-hex-4-enoic acid methyl ester 
• 219585-90-7 (S)-2-Benzyloxycarbonylamino-2-isobutyl-5-methyl-hex-4-enoic acid methyl ester 

Downstream Products

• 288404-46-6 ((S)-3-Isobutyl-2-oxo-tetrahydro-furan-3-yl)-carbamic acid benzyl ester 
• 219585-92-9 (2S,5'S)-5'-[2-Hydroxy-3-(toluene-4-sulfonyloxy)-propyl]-2,5'-diisobutyl-4-[(R)-3-methyl-1-(2-trimethylsilanyl-ethoxymethoxymethyl)-butyl]-3,4'-dioxo-2,3,4',5'-tetrahydro-[2,3']bipyrrolyl-1,1'-dicarboxylic acid diallyl ester 
• 288404-56-8 2-tert-butoxycarbonylamino-2-[5''-(2-hydroxy-ethyl)-5',5''-diisobutyl-2-isopropyl-3,4',4''-trioxo-2,3,4',5',4'',5''-hexahydro-1H,1'H,1''H-[2,3';5',3'']terpyrrol-4-yl]-3-phenyl-propionic acid methyl ester 
• 288404-55-7 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S)-5'-(2-hydroxy-ethyl)-5'-isobutyl-2-isopropyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 
• 288403-75-8 (S)-3-Amino-3-isobutyl-dihydro-furan-2-one 
• 159216-07-6 CHCH₂CCOCH₂C₆H₅NCO₂C₄H₉NCC₃H₇COCCHNHCC₄H₉CH₂COHCONCC₄H₉COCH₂CNCCH₂C₆H₅COCH₃CH₂CHC₃H₅ 
• 159216-06-5 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S,5''S)-5',5''-diisobutyl-2-isopropyl-3,4',4''-trioxo-5''-(2-oxo-ethyl)-2,3,4',5',4'',5''-hexahydro-1H,1'H,1''H-[2,3';5',3'']terpyrrol-4-yl]-3-phenyl-propionic acid methyl ester 
• 145452-13-7 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S)-5'-isobutyl-2-isopropyl-3,4'-dioxo-5'-(2-oxo-ethyl)-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 

Relevant academic research and scientific papers

A second-generation synthesis of polypyrrolinone nonpeptidomimetics: prelude to the synthesis of polypyrrolinones on solid support.

[reaction: see text] A second-generation asymmetric synthesis of polypyrrolinones (3) has been achieved exploiting scalemic alpha-aminolactones (1) as building blocks. Imine formation between an appropriate lactone (1) and aldehyde (2), followed in turn b