219633-70-2Relevant academic research and scientific papers
Interchangeability of halogen and ethynyl substituents in the solid state structures of di- and tri-substituted benzenes
Robinson, James M. A.,Kariuki, Benson M.,Harris, Kenneth D. M.,Philp, Douglas
, p. 2459 - 2469 (2007/10/03)
Examination of the solid state structures of bromo- and fluoro-substituted ethynylbenzenes, determined by single crystal X-ray diffraction, has demonstrated that the halogen and ethynyl substituents on these 1,4- and 1,3,5-substituted benzene rings can be interchanged without significant changes in their average solid state structures. Consideration of these structures, together with those of 1,4- and 1,3,5-substituted halogenobenzenes, suggests that, in most cases, shape complementarity may be of equal importance to interactional complementarity when attempting to rationalise the packing of these molecules in the solid state.
Multiply bridged acetylenic thiacyclophanes
Ensley, Harry E.,Mahadevan, Shivkumar,Mague, Joel
, p. 6255 - 6258 (2007/10/03)
The 4,17,30-trithia-[73](1,3,5)cyclophane (1) has been prepared by a two-stage, palladium assisted coupling of propargylOTHP with 1,3,5-tribromobenzene, followed by sulfide ring closure. The intermediate (8) on deprotection, followed by bromination and reaction with Na2S gives 1 in 58% yield.
