219691-98-2Relevant academic research and scientific papers
Novel Phosphinic Acid-Containing Thyromimetics
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Page/Page column 137, (2009/02/11)
The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome x and diabetes.
NOVEL PHOSPHORUS-CONTAINING THYROMIMETICS
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Page/Page column 280, (2008/06/13)
The present invention relates to compounds of phosphonic acid containing T3 mimetics, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndromex and diabetes.
Thyroid receptor ligands and method
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, (2008/06/13)
Novel thyroid receptor ligands are provided which have the general formula (I) where R1is alkyl of 1 to 4 carbons or cycloalkyl of 3 to 7 carbons; R2and R3are the same or different and are hydrogen, halogen, alkyl of 1 to
