219701-26-5Relevant academic research and scientific papers
Electrochemical oxidation of 4-monoalkyl-substituted 1,4-dihydropyridines
Turovska,Goba,Turovskis,Grinberga,Belyakov,Stupnikova,Liepinsh,Stradins
, p. 1483 - 1490 (2008)
The electrochemical oxidation of 4-monoalkyl-substituted 1,4-dihydropyridines has been studied in an aprotic medium and in the presence of pyridine. In an aprotic medium the products of oxidation are both 4-alkyl-substituted and 4-unsubstituted pyridines
Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: A chemical model for possible biologically relevant properties of molybdenum-containing enzymes
Litvic, Mladen,Regovic, Maja,Smic, Karolina,Lovric, Marija,Filipan-Litvic, Mirela
experimental part, p. 3676 - 3681 (2012/07/17)
Mo(VI) and Mo(V) salts both react selectively with Hantzsch esters to produce substitute pyridines in good-to-excellent yield (75-99%). The remarkable reactivity and selectivity of MoOCl4 under reflux of acetonitrile and MoCl5 in dichloromethane at room temperature encouraged us to propose that molybdenum-containing enzymes (such as xanthine or aldehyde oxidase) also participate to some degree in the metabolism of 1,4-dihydropyridine drugs in the liver analogous to NADH in the respiratory chain.
