219706-58-8Relevant academic research and scientific papers
Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture
Nasim, Shama,Guzman, Monica L.,Jordan, Craig T.,Crooks, Peter A.
scheme or table, p. 4879 - 4883 (2011/09/16)
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione (TDZD-8) was previously identified as an antileukemic agent exhibiting no evident toxicity toward normal hematopoietic cells. An SAR study has been carried out to examine the effect of varying the C-2 and
