219720-86-2

Upstream product

• 121845-98-5 (3aR,4S,6R,6aS)-6-(3-(4-methoxybenzyl)-3,4-dihydro-2,4-dioxopyrimidin-1(2H)-yl)-tetrahydro-2,2-dimethylfuro[3,4-d][1,3]dioxole-4-carbaldehyde 
• 170936-40-0 (6S,7R)-7-Benzyloxymethyl-6-(tert-butyl-diphenyl-silanyloxy)-1,4-dimethyl-[1,4]diazepan-2-one 

Downstream Products

• 219720-82-8 1-((R)-1-{(1S,2S)-2-[(2S,5R,6S)-5-Benzyloxymethyl-6-(tert-butyl-diphenyl-silanyloxy)-1,4-dimethyl-3-oxo-[1,4]diazepan-2-yl]-2-hydroxy-1-hydroxymethyl-ethoxy}-2-hydroxy-ethyl)-3-(4-methoxy-benzyl)-1H-pyrimidine-2,4-dione 
• 219720-80-6 (2R,3S)-3-[(2S,5R,6S)-5-Benzyloxymethyl-6-(tert-butyl-diphenyl-silanyloxy)-1,4-dimethyl-3-oxo-[1,4]diazepan-2-yl]-3-hydroxy-2-{(R)-1-[3-(4-methoxy-benzyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-2-oxo-ethoxy}-propionaldehyde 
• 219720-79-3 1-((2R,3R,4S,5R)-5-{(S)-[(2S,5R,6S)-5-Benzyloxymethyl-6-(tert-butyl-diphenyl-silanyloxy)-1,4-dimethyl-3-oxo-[1,4]diazepan-2-yl]-hydroxy-methyl}-3,4-dihydroxy-tetrahydro-furan-2-yl)-3-(4-methoxy-benzyl)-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Synthesis of the diazepanone-nucleoside portion of liposidomycins by aldol reaction of the enolate of diazepanone with a nucleoside 5'-aldehyde

The diazepanone-nucleoside part of liposidomycins has been synthesized by the aldol reaction between the enolate of a stereochemically defined diazepanone and a uridine 5'-aldehyde. The configurations of two new stereocenters in the aldol product have bee