219763-85-6 Usage
General Description
Methyl 4-bromoquinoline-6-carboxylate is a synthetic chemical compound with the molecular formula C11H8BrNO2. It belongs to the chemical class of quinolines, which are heterocyclic aromatic organic compounds. This particular compound is used in the field of organic synthesis, often as a building block in the production of more complex chemical structures. With its bromine atom, it can undergo various reactions to create a wide range of products. Its properties such as boiling point, melting point, and solubility can vary depending on structural modifications during synthesis. It's advisable to handle it with care due to its potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 219763-85-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,7,6 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 219763-85:
(8*2)+(7*1)+(6*9)+(5*7)+(4*6)+(3*3)+(2*8)+(1*5)=166
166 % 10 = 6
So 219763-85-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H8BrNO2/c1-15-11(14)7-2-3-10-8(6-7)9(12)4-5-13-10/h2-6H,1H3
219763-85-6Relevant articles and documents
Assembly of 4-aminoquinolines via palladium catalysis: A mild and convenient alternative to SNAr methodology
Margolis, Brandon J.,Long, Kimberly A.,Laird, Dana L. T.,Ruble, J. Craig,Pulley, Shon R.
, p. 2232 - 2235 (2007/10/03)
4-Aminoquinolines, classically prepared via SNAr chemistry from an amine and 4-haloquinoline, are important scaffolds in medicinal chemistry. Interest in these compounds prompted us to explore palladium catalysis as an alternative to the existing methods for their preparation. Initial results followed by an iterative screening paradigm confirmed Pd(OAc)2/ DPEphos/K3PO4 as a mild and convenient alternative for the formation of the C-N bond in 4-aminoquinolines. A description of the screen and the scope of this methodology are discussed herein.
