219783-77-4

Basic information

• Product Name: Paclitaxel IMpurity O
• Synonyms: Paclitaxel IMpurity O;N-Cinnamoyl N-Debenzoyl Paclitaxel;Paclitaxel EP Impurity O
• CAS NO: 219783-77-4
• Molecular Formula: C49H53NO14
• Molecular Weight: 879.96
• Mol File: 219783-77-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 149-150 °C
• Boiling Point: 982.1±65.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• PKA: 11.91±0.20(Predicted)
• CAS DataBase Reference: Paclitaxel IMpurity O(CAS DataBase Reference)
• NIST Chemistry Reference: Paclitaxel IMpurity O(219783-77-4)
• EPA Substance Registry System: Paclitaxel IMpurity O(219783-77-4)

Safety Data

• Hazardous Substances Data: 219783-77-4(Hazardous Substances Data)

Usage

Description

Paclitaxel IMpurity O, also known as Paclitaxel EP Impurity O, is an impurity found in Paclitaxel (P132500), a widely used antineoplastic drug. It is derived from the bark of the Pacific yew tree and has gained significant attention due to its potential role in cancer treatment.

Uses

Used in Pharmaceutical Industry:
Paclitaxel IMpurity O is used as an impurity in the production of Paclitaxel, an antineoplastic agent. It is utilized for the treatment of various types of cancer, including lung, ovarian, breast, head and neck cancer, and advanced forms of Kaposi's sarcoma. The presence of this impurity in Paclitaxel may affect the drug's efficacy and safety, making it crucial to monitor and control its levels during the manufacturing process.
Used in Cancer Treatment:
Paclitaxel IMpurity O, as a component of Paclitaxel, plays a role in the treatment of cancer by targeting and disrupting the microtubules within cancer cells. This action leads to the prevention of cell division and ultimately results in cell death. The impurity may also contribute to the overall effectiveness of the drug, although its specific impact on cancer treatment is not well-defined and requires further research.
Used in Research and Development:
Paclitaxel IMpurity O serves as a valuable compound for researchers in the field of cancer therapeutics. It can be used to study the mechanisms of action, drug interactions, and potential side effects of Paclitaxel. Understanding the role of this impurity in the overall efficacy and safety profile of Paclitaxel can help in the development of more effective and safer cancer treatments.