219801-55-5Relevant academic research and scientific papers
Total synthesis of (-)-γ-lycorane using diastereoselective 5-endo-trig radical cyclization of N-vinylic α-halo amides
Ikeda, Masazumi,Ohtani, Shinji,Sato, Tatsunori,Ishibashi, Hiroyuki
, p. 1803 - 1806 (1998)
Bu3SnH-mediated radical cyclization of α-iodo-N-(6-oxocylohex-1- enyl)-N-[(S)-1-phenylethyl]acetamide (6) proceeded in a 5-endo-trig manner with moderate diastereoselectivity to give (3aS, 7aR)-octahydroindole-2,7- dione 8a as the major product
