219812-89-2Relevant academic research and scientific papers
Polyol-amino acid compounds having anti-helicobacter pylori activity
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, (2008/06/13)
A compound of the formula (I): wherein R1represents an amino group which may be substituted; R2represents a carboxy group which may be esterified or amidated; R3, R4, R5and R6each represent a hydroxy group which may be protected; Q represents an aryl group which may be substituted; or a salt thereof is disclosed. The compound (I) possesses ant-Helicobacter pyloriactivity, and is useful in the prevention or treatment of various diseases associated with Helicobacter bacteria, such as duodenal ulcer, gastric ulcer, chronic gastritis and cancer of the stomach.
