21983-08-4Relevant academic research and scientific papers
Base-Free Direct Synthesis of Alkynylphosphonates from Alkynes and H-Phosphonates Catalyzed by Cu2O
Moglie, Yanina,Mascaró, Evangelina,Gutierrez, Victoria,Alonso, Francisco,Radivoy, Gabriel
, p. 1813 - 1818 (2016)
A simple and mild methodology for the direct synthesis of alkynylphosphonates is presented. The reaction of a variety of terminal alkynes with dialkyl phosphites in the presence Cu2O (14 mol %) led to the formation of the corresponding alkynylp
Aerobic oxidative alkynylation of H-phosphonates and amides: An efficient route for the synthesis of alkynylphosphonates and ynamides using a recyclable Cu-MnO catalyst
Singh, Harshvardhan,Sahoo, Tapan,Sen, Chiranjit,Galani, Sunil M.,Ghosh, Subhash Chandra
, p. 1691 - 1698 (2019/04/08)
An atom-economical and efficient route for the synthesis of alkynylphosphonates and ynamides by aerobic oxidative alkynylation of H-phosphonates and amides with both aliphatic and aromatic alkynes using our synthesized recyclable heterogeneous Cu-MnO catalyst has been developed. The phosphorylation was carried out under base- and ligand-free conditions, and in the presence of air as the sole oxidant. The reaction is compatible with a wide variety of functional groups and generates alkynylphosphonate and ynamide products in good to excellent yields. Both reactions can be scaled up to the gram scale without any decrease in the reaction yield and the reaction time is less compared to literature reports. The catalyst is recyclable and reused several times without any significant loss of reactivity.
Synthetic method of alkynyl phosphate
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Paragraph 0059; 0060; 0061; 0062; 0063, (2017/10/31)
The invention provides a synthetic method of alkynyl phosphate. The synthetic method comprises the steps of dissolving alkyne, hydrogen phosphonate and a photocatalyst into an organic solvent to obtain a mixed solution, adding a catalytic amount of copper
