219869-44-0

Basic information

• Product Name: 2-Oxa-6-azaspiro[3.4]octan-8-aMine, 6-(phenylMethyl)-
• Synonyms: 2-Oxa-6-azaspiro[3.4]octan-8-aMine, 6-(phenylMethyl)-;6-benzyl-2-oxa-6-azaspiro[3.4]octan-8-aMine
• CAS NO: 219869-44-0
• Molecular Formula: C13H18N2O
• Molecular Weight: 218.29482
• Mol File: 219869-44-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 336°C at 760 mmHg
• Flash Point: 157°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.000115mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: 2-Oxa-6-azaspiro[3.4]octan-8-aMine, 6-(phenylMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxa-6-azaspiro[3.4]octan-8-aMine, 6-(phenylMethyl)-(219869-44-0)
• EPA Substance Registry System: 2-Oxa-6-azaspiro[3.4]octan-8-aMine, 6-(phenylMethyl)-(219869-44-0)

Safety Data

• Hazardous Substances Data: 219869-44-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H18N2O/c14-12-7-15(8-13(12)9-16-10-13)6-11-4-2-1-3-5-11/h1-5,12H,6-10,14H2

Relevant articles and documents

Synthesis method of tert-butyl 2-oxa-6-azaspiro[3.4]octan-8-yl carbamate

The invention discloses a synthesis method of tert-butyl 2-oxa-6-azaspiro[3.4]octan-8-yl carbamate, which comprises the following steps: step 1, reducing nitryl of a compound 1 into amino under the catalysis of nickel to obtain a compound 2; step 2, reacting the compound 2 with (Boc)2O to add a Boc protecting group on the amino group to obtain a compound 3; and step 3, carrying out catalytic hydrogenation on the compound 3 to remove benzyl so as to obtain a compound 4. The method disclosed by the invention has the advantages of easily available raw materials, convenience in operation, safety in reaction, easiness in control, suitability for amplification, short route, higher total yield, suitability for industrial production and the like.