219906-61-3Relevant academic research and scientific papers
A novel and highly regioselective approach to 5-methoxy-6-substituted-3- sulfonyl-δ-enlactams from 5-methoxy-3-sulfonyl glutarimide: Synthesis of cis-2-substituted-3-piperidinols
Tsai, Min-Ruei,Chen, Bo-Fong,Cheng, Chih-Ching,Chang, Nein-Chen
, p. 1780 - 1785 (2007/10/03)
(Chemical Equation Presented) A convenient method for the preparation of 5-methoxy-6-substituted-3-sulfonyl-δ-enlactams via regioselective nucleophilic addition to 5-methoxy-3-sulfonyl glutarimide is described. Formal syntheses of L-733,060, CP-99,994, an
Unexpected enolization of 2-phenyl-3-piperidone derivatives
Daley, Valérie,Cavé, Christian,D'Angelo, Jean
, p. 2157 - 2162 (2007/10/03)
Alkylation of 2-phenyl-3-piperidone (17) with methyl iodide or methyl acrylate furnished the 4,4-dialkylated derivatives (18) or (19), respectively. This unexpected enolization towards the less substituted form can be interpreted considering the appreciab
