219908-81-3Relevant academic research and scientific papers
Double diastereocontrol in the synthesis of enantiomerically pure polyoxamic acid
Harwood, Laurence M.,Robertson, Sarah M.
, p. 2641 - 2642 (1998)
Polyoxamic acid 4 is prepared by a short and efficient process involving diastereochemically matched cycloaddition of 5-(S)-phenylmorpholin-2-one 1 with (S)-glyceraldehyde acetonide 2, followed by sequential hydrolysis and hydrogenolysis of the adduct.
