219920-69-1Relevant articles and documents
Design, synthesis and evaluation of carbamate-modified (-)-N1-phenethylnorphysostigmine derivatives as selective butyrylcholinesterase inhibitors
Takahashi, Jun,Hijikuro, Ichiro,Kihara, Takeshi,Murugesh, Modachur G.,Fuse, Shinichiro,Tsumura, Yoshinori,Akaike, Akinori,Niidome, Tetsuhiro,Takahashi, Takashi,Sugimoto, Hachiro
scheme or table, p. 1721 - 1723 (2010/06/19)
We synthesized carbamate-modified (-)-N1-phenethylnorphysostigmine derivatives 3a-u and evaluated their anti-cholinesterase activities. In vitro evaluation showed that cyclohexylmethylcarbamate derivative 3u potently and selectively inhibits bu