219921-68-3

Basic information

• Product Name: 5-AMINO-2-(1-PYRROLIDINYL)BENZONITRILE
• Synonyms: 5-AMINO-2-(1-PYRROLIDINYL)BENZONITRILE;5-amino-2-(1-pyrrolidinyl)benzonitrile(SALTDATA: FREE);5-AMino-2-(pyrrolidin-1-yl)benzonitrile
• CAS NO: 219921-68-3
• Molecular Formula: C₁₁H₁₃N₃
• Molecular Weight: 187.25
• Mol File: 219921-68-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 422.573°C at 760 mmHg
• Flash Point: 209.365°C
• Appearance: /
• Density: 1.194g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 5-AMINO-2-(1-PYRROLIDINYL)BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-2-(1-PYRROLIDINYL)BENZONITRILE(219921-68-3)
• EPA Substance Registry System: 5-AMINO-2-(1-PYRROLIDINYL)BENZONITRILE(219921-68-3)

Safety Data

• Hazardous Substances Data: 219921-68-3(Hazardous Substances Data)

Usage

Uses

5-Amino-2-(pyrrolidin-1-yl)benzonitrile is a useful reagent in the preparation of antidiabetic repaglinide and other related benzoic acid derivatives.

InChI:InChI=1/C11H13N3/c12-8-9-7-10(13)3-4-11(9)14-5-1-2-6-14/h3-4,7H,1-2,5-6,13H2

Upstream product

• 17615-42-8 1-pyrrolidino-4-nitro-2-cyanobenzene 
• 16588-02-6 4-chloro-3-cyanonitrobenzene 

Downstream Products

• 288250-73-7 1-(4-chlorophenyl)-N-(3-cyano-4-pyrrolidinophenyl)-5-methylpyrazole-4-carboxamide 
• 288250-72-6 N-(3-cyano-4-pyrrolidinophenyl)-1-(4-fluorophenyl)-5-methylpyrazole-4-carboxamide 
• 83894-71-7 methyl 4-<2-<<1-<5-chloro-2-(1-pyrrolidinyl)phenyl>ethyl>amino>-2-oxoethyl>-benzoate 
• 1027958-07-1 1-(5-chloro-2-pyrrolidin-1-yl-phenyl)-ethylideneamine 
• 219921-67-2 1-(5-chloro-2-pyrrolidino-phenyl)-ethylamine 
• 219921-69-4 5-chloro-2-pyrrolidino-benzonitrile 

Relevant articles and documents

AMIDE COMPOUNDS AND MEDICINAL USE THEREOF

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X' is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.