21994-41-2

Usage

Uses

Used in Coordination Chemistry:
1-(4-cyanobutyl)triaza-1,2-dien-2-ium is used as a ligand in coordination chemistry for its ability to form stable complexes with metal ions. The presence of the cyano group and the butyl chain allows for versatile coordination modes, enhancing the stability and reactivity of the resulting metal complexes.
Used in Organic Synthesis:
In the field of organic synthesis, 1-(4-cyanobutyl)triaza-1,2-dien-2-ium is used as a precursor for the synthesis of other organic compounds. Its unique structure and reactivity make it a valuable building block for creating a wide range of molecules with diverse applications, such as pharmaceuticals, agrochemicals, and advanced materials.
Used in Pharmaceutical Industry:
1-(4-cyanobutyl)triaza-1,2-dien-2-ium is used as a key intermediate in the development of new pharmaceuticals. Its unique molecular structure can be exploited to design and synthesize novel drug candidates with improved potency, selectivity, and pharmacokinetic properties.
Used in Material Science:
In the material science industry, 1-(4-cyanobutyl)triaza-1,2-dien-2-ium can be used as a component in the development of advanced materials with specific properties, such as conductivity, magnetism, or optical activity. Its incorporation into polymers, nanoparticles, or other composite materials can lead to the creation of materials with enhanced performance and novel applications.
Used in Analytical Chemistry:
1-(4-cyanobutyl)triaza-1,2-dien-2-ium can be employed as a reagent or a sensing element in analytical chemistry. Its unique chemical properties and reactivity can be utilized to develop new methods for the detection, quantification, or separation of various analytes, contributing to the advancement of analytical techniques and technologies.

Upstream product

• 5414-21-1 5-bromopentan-1-nitrile 
• 6280-87-1 δ-chlorovaleronitrile 

Downstream Products

• 7465-48-7 Tetramethylenetetrazole 
• 353-13-9 5-fluoro-valeronitrile 
• 58793-94-5 4-Fluorpentannitril 
• 6066-83-7 5-Aminopentanenitrile 
• 328400-62-0 benzyl (4-cyanobutyl)carbamate 
• 875932-93-7 [4-(1H-tetrazol-5-yl)-butyl]-carbamic acid benzyl ester 
• 79583-98-5 5-azidovaleric acid 
• 1619226-23-1 C₁₅H₁₈N₄O₂ 
• 1619226-25-3 C₃₂H₃₈N₈O₄ 

Relevant academic research and scientific papers

A γ-ray and dual redox-responsive supramolecular polymer constructed by a selenium containing pillar[5]arene dimer and a neutral guest

The first γ-radiation responsive linear supramolecular via pillararene-based host-guest recognition polymer was built successfully. What is more, this supramolecular polymer exhibited dual redox responsiveness.

Supramolecular polymers based on efficient pillar[5]arene - Neutral guest motifs

Neutral and efficient: A neutral guest with a cyano site and a triazole site, which can be easily prepared and modified, is demonstrated to strongly bind with pillar[5]arene (see figure). Based on this new recognition motif, two neutral supramolecular pol

Mild Synthesis of Pillar[4]arene[1]cis-diepoxy-p-dione and Guest-Assisted Formation of a 2D Network in the Solid State

Herein, we developed an environmentally friendly, feasible method to synthesize pillar[4]arene[1]cis-diepoxy-p-dione. Strikingly, single-crystal X-ray analysis of pillar[4]arene[1]cis-diepoxy-p-dione and 5-chloropentanenitrile indicated a 1:2 stoichiometry to form a 2D network in the solid state.

Ytterbium-Catalyzed Intramolecular [3 + 2] Cycloaddition based on Furan Dearomatization to Construct Fused Triazoles

The 1,2,3-triazole-containing polycyclic architecture widely exists in a broad spectrum of synthetic bioactive molecules, and the development of expeditious methods to synthesize these skeletons remains a challenging task. In this work, the catalytic cyclization of biomass-derived 2-furylcarbinols with an azide to form fused triazoles is described. This approach takes advantage of a single catalyst Yb(OTf)3 and operates via a furfuryl-cation-induced intramolecular [3 + 2] cycloaddition/furan ring-opening cascade.

Artificial light-harvesting supramolecular polymeric nanoparticles formed by pillar[5]arene-based host-guest interaction

Artificial light-harvesting nanoparticles were prepared from supramolecular polymers comprised of pillar[5]arene with anthracene-derived donors and acceptors through host-guest interactions. The resulting water-dispersible nanoparticles displayed efficient energy transfer and excellent light harvesting ability in part because the steric bulk of pillar[5]arene suppressed the self-quenching of the chromophores.

Acid/Base-Controllable FRET and Self-Assembling Systems Fabricated by Rhodamine B Functionalized Pillar[5]arene-Based Host-Guest Recognition Motifs

A novel supramolecular F?ster resonance energy transfer (FRET) system was fabricated by utilizing rhodamine B (RB) functionalized pillar[5]arene (EtP5-RB) and cyano-modified boron dipyrromethene (BDP-CN) based on their host-guest recognition at 5.0 × 10s

Stronger host-guest binding does not necessarily give brighter particles: a case study on polymeric AIEE-tunable and size-tunable supraspheres

Supraspheres were prepared from a pillar[5]arene-based linear polymer (the host) and several multitopic guests. According to host-guest binding studies in nanosystems, the optical and structural properties (fluorescence capability, density, and particle s

In situ supramolecular polymerization promoted by the marriage of dynamic covalent bonding and pillar[5]arene-based host-guest interaction

In situ fabrication of a temperature and pH dual-responsive linear supramolecular polymer through the marriage of dynamic covalent bonding and pillar[5]arene-based host-guest interaction was investigated.

Synthesis and Evaluation of a Library of Trifunctional Scaffold-Derived Compounds as Modulators of the Insulin Receptor

We designed a combinatorial library of trifunctional scaffold-derived compounds, which were derivatized with 30 different in-house-made azides. The compounds were proposed to mimic insulin receptor (IR)-binding epitopes in the insulin molecule and bind to and activate this receptor. This work has enabled us to test our synthetic and biological methodology and to prove its robustness and reliability for the solid-phase synthesis and testing of combinatorial libraries of the trifunctional scaffold-derived compounds. Our effort resulted in the discovery of two compounds, which were able to weakly induce the autophosphorylation of IR and weakly bind to this receptor at a 0.1 mM concentration. Despite these modest biological results, which well document the well-known difficulty in modulating protein-protein interactions, this study represents a unique example of targeting the IR with a set of nonpeptide compounds that were specifically designed and synthesized for this purpose. We believe that this work can open new perspectives for the development of next-generation insulin mimetics based on the scaffold structure.

Formation of fluorescent supramolecular polymeric assemblies via orthogonal pillar[5]arene-based molecular recognition and metal ion coordination

A fluorescent supramolecular polymer was efficiently constructed by pillar[5]arene-based host-guest molecular recognition and zinc ion coordination. This journal is