219992-65-1

Upstream product

• 2048-50-2 benzyloxyurea 
• 622-33-3 N-benzyloxyamine 

Downstream Products

• 189497-16-3 4-[5-(methyloxycarbonyl)-pentylamino]-1-(benzyloxy)-2(1H)-pyrimidinone 
• 189497-19-6 4-{[6-(methoxycarbonyl)hexyl]amino}-1-(benzyloxy)-2(1H)-pyrimidinone 
• 219992-67-3 N-(1-benzyloxy-2-oxo-1,2-dihydropyrimidin-4-yl)-N'-(tert-butoxycarbonyl)ethane-1,2-diamine 
• 219992-69-5 N-(1-benzyloxy-2-oxo-1,2-dihydropyrimidin-4-yl)-N'-(tert-butoxycarbonyl)butane-1,4-diamine 
• 219992-71-9 N-(1-benzyloxy-2-oxo-1,2-dihydropyrimidin-4-yl)-N'-(tert-butoxycarbonyl)hexane-1,6-diamine 
• 522644-14-0 N^α-tert-butoxycarbonyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysine methyle ester 
• 522644-22-0 N^α-tert-butoxycarbonyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysine 
• 522644-15-1 N^α-tert-butoxycarbonyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanine methyl ester 
• 522644-16-2 N^α-tert-butoxycarbonyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanine 
• 522644-18-4 N^α-tert-butoxycarbonyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanine methyl ester 
• 522644-19-5 N^α-tert-butoxycarbonyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanyl N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanyl-N^ε-(1-benzyloxy-1,2-dihydro-2-oxopyrimidin-4-yl)-L-lysyl-β-alanine methyl ester 
• 522644-28-6 C₆₅H₈₅N₁₅O₁₅ 
• 1236865-24-9 4-{5-[2-(4-sulfamoyl-phenyl)-ethyl-carbamoyl]pentylamino}-1-(benzyloxy)-2(1H)-pyrimidinone 
• 1236865-20-5 4-{3-[(4-sulfamoyl-phenyl)carbamoyl]propylamino}-1-(benzyloxy)-2(1H)-pyrimidinone 

Relevant academic research and scientific papers

Synthesis of N-1-oxypyrimidine 1,3-dioxolane and 1,3-oxathiolane nucleosides

Two series of 1,3-dioxolanes and 1,3-oxathiolane nucleosides containing N-1-oxypyrimidine were synthesized as potential antiviral agents.

Novel Iron Sequestering Agents: Synthesis and Iron-Chelating Properties of Hexadentate Ligands Composed of 1-Hydroxy-2(1H)-pyrimidinone, ω-Amino Carboxylic Acid, and Tris(2-aminoethyl)amine

Novel heterocyclic hexadentate ligands (3HOPYn: n = 5-7), in which three units of 1-hydroxy-2(1H)-pyrimidinone are linked to tris(2-aminoethyl)amine through an amide bond by an alkyl chain, were synthesized, and their iron-chelating properties were investigated. The stability of their iron complexes (25 to 27 in log K) was significantly larger than that of pyrazinone-containing ligands by virtue of higher pKa values. On kinetic evaluation of iron removal from human transferrin, 3HOPY5 showed remarkable efficiency over five times as much as commercially available desferrioxamine B. The conformational analysis of the corresponding Ga(III) complex of Fe(opy5) by 1H NMR and by MM and MD calculations are also discussed.