219998-99-9

Upstream product

• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 122283-38-9 (E)-2-(2-Bromo-phenyl)-3-methoxy-acrylic acid methyl ester 
• 219998-98-8 methyl (E)-3-methoxy-2-{(E)-2-[3(RS)-(tetrahydropyran-2-yloxy)propenyl]phenyl}acrylate 

Downstream Products

• 262268-39-3 methyl (E)-2-[2-[(E)-3-bromopropenyl]phenyl]-3-methoxyacrylate 

Relevant academic research and scientific papers

beta -Alkoxyacrylates against malaria

The present invention relates to compounds having the formulae wherein R, R1, R6, R7, Rn8, X, and Z are defined herein, which are useful in the treatment or prophylaxis of malaria. The compounds of the present invention are especially useful in the treatm

Phenyl β-methoxyacrylates: A new antimalarial pharmacophore

Phenyl β-methoxyacrylates, linked to an aromatic ring via an olefinic bridge, have been identified as novel, potentially inexpensive, antimalarial agents. The compounds are believed to exert their activity by inhibition of mitochondrial electron transport