22002-17-1

Basic information

• Product Name: 3,5-DICHLORO-4-HYDROXYBENZYL ALCOHOL
• Synonyms: 3,5-DICHLORO-4-HYDROXYBENZYL ALCOHOL;RARECHEM AL BD 0933
• CAS NO: 22002-17-1
• Molecular Formula: C₇H₆Cl₂O₂
• Molecular Weight: 193.03
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 22002-17-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 296.6°C at 760 mmHg
• Flash Point: 133.2°C
• Appearance: /
• Density: 1.537g/cm³
• Vapor Pressure: 0.00064mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 3,5-DICHLORO-4-HYDROXYBENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICHLORO-4-HYDROXYBENZYL ALCOHOL(22002-17-1)
• EPA Substance Registry System: 3,5-DICHLORO-4-HYDROXYBENZYL ALCOHOL(22002-17-1)

Safety Data

• Hazardous Substances Data: 22002-17-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6Cl2O2/c8-5-1-4(3-10)2-6(9)7(5)11/h1-2,10-11H,3H2

Upstream product

• 87-65-0 2,6-Dichlorophenol 
• 2314-36-5 3,5-dichloro-4-hydroxybenzaldehyde 
• 17302-82-8 ethyl 3,5-dichloro-4-hydroxybenzoate 
• 3337-59-5 methyl 3,5-dichloro-4-hydroxybenzoate 
• 79817-04-2 (3,5-dichloro-4-hydroxybenzyl)pyridinium chloride 
• 50-00-0 formaldehyd 
• 857537-88-3 4-acetoxy-3,5-dichloro-benzoic acid ethyl ester 
• 3336-41-2 3,5-dichloro-4-hydroxybenzoic acid 

Downstream Products

• 3933-88-8 3,3',5,5'-Tetrachlor-4,4'-dihydroxydiphenylmethan 
• 55008-59-8 bis-(3,5-dichloro-4-hydroxy-benzyl)-ether 
• 2314-36-5 3,5-dichloro-4-hydroxybenzaldehyde 
• 85628-45-1 2,6-Dichlor-4-(2-methyl-2-nitropropyl)phenol 
• 76890-93-2 4,4’-dihydroxydibenzyl ether 
• 158692-34-3 ethyl 2-(2,6-dichloro-4-hydroxymethylphenoxy)-2-(3,4-methylenedioxyphenyl) acetate 
• 73049-09-9 1-(3,5-dichloro-4-hydroxyphenyl)-2-phenylethanol 
• 73048-86-9 benzyl 3,5-dichloro-4-hydroxyphenyl ketone 
• 85628-62-2 3,5-Dichlor-4-methoxy-(2-amino-2-methylpropyl)benzol 
• 85628-51-9 3,5-Dichlor-4-methoxy-(2-methyl-2-nitropropyl)benzol 
• 85628-57-5 2,6-Dichlor-4-(2-amino-2-methylpropyl)phenol 
• 212067-18-0 (R,S)-N-acetyl-α-(3,5-dichloro-4-hydroxyphenyl)glycine 

Relevant articles and documents

CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE

The invention provides a class of compounds represented by formula (I), having bifunctional active quaternary ammonium salt structure of a β2-adrenoreceptor agonist and an M receptor antagonist, a pharmaceutically acceptable salt, solvate, and optical isomer thereof. A pharmaceutical composition comprising such a compound with quaternary ammonium salt structure, a method for preparing such a compound with quaternary ammonium salt structure and an intermediate thereof, and uses thereof in treating pulmonary disorders are also provided. The compounds of the invention have high selectivity to the M receptor subtype, and have less adverse reaction and lower toxic and side effects in the treatment of pulmonary diseases such as COPD and asthma.

BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS

The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.

BICYCLIC FIVE-MEMBERED HETEROARYL DERIVATIVES AND THEIR USE AS RENIN INHIBITORS

The invention relates to novel five-membered heteroaryl derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions comprising one or more of those compounds and especially their use as inhibitors of renin.