220023-64-3Relevant academic research and scientific papers
Total syntheses of (+)-azimic acid, (+)-julifloridine, and proposed structure of N-methyljulifloridine via cyeloaddition of nitrone to a chiral dipolarophile
Kiguchi, Toshiko,Shirakawa, Mitsuko,Honda, Rina,Ninomiya, Ichiya,Naito, Takeaki
, p. 15589 - 15606 (2007/10/03)
A combination of 1,3-dipolar cycloaddition of Z-nitrones to the chiral dipolarophile and subsequent ring transformation of the resulting adducts to the piperidinols has provided a new practical synthesis of 2,6-disubstituted 3-piperidinol alkaloids, (+)-azimic acid, (+)-julifloridine, and the proposed structure of N-methyljulifloridine.
