220024-45-3

Basic information

• Product Name: 6-{(3S,5R)-2-Benzyl-5-[(1R,2R)-2-hydroxy-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester
• Synonyms: 6-{(3S,5R)-2-Benzyl-5-[(1R,2R)-2-hydroxy-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester
• CAS NO: 220024-45-3
• Molecular Weight: 453.576
• Mol File: 220024-45-3.mol

Chemical Properties

• CAS DataBase Reference: 6-{(3S,5R)-2-Benzyl-5-[(1R,2R)-2-hydroxy-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{(3S,5R)-2-Benzyl-5-[(1R,2R)-2-hydroxy-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester(220024-45-3)
• EPA Substance Registry System: 6-{(3S,5R)-2-Benzyl-5-[(1R,2R)-2-hydroxy-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester(220024-45-3)

Safety Data

• Hazardous Substances Data: 220024-45-3(Hazardous Substances Data)

Upstream product

• 179462-39-6 6-{(3S,5R)-2-Benzyl-5-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester 
• 220046-46-8 6-{(3S,5R)-2-Benzyl-5-[(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester 

Downstream Products

• 220023-67-6 6-{(3S,5R)-2-Benzyl-5-[(1S,2R)-2-methanesulfonyloxy-1-(2-methoxy-ethoxymethoxy)-propyl]-isoxazolidin-3-yl}-hexanoic acid methyl ester 

Relevant articles and documents

Total syntheses of (+)-azimic acid, (+)-julifloridine, and proposed structure of N-methyljulifloridine via cyeloaddition of nitrone to a chiral dipolarophile

A combination of 1,3-dipolar cycloaddition of Z-nitrones to the chiral dipolarophile and subsequent ring transformation of the resulting adducts to the piperidinols has provided a new practical synthesis of 2,6-disubstituted 3-piperidinol alkaloids, (+)-azimic acid, (+)-julifloridine, and the proposed structure of N-methyljulifloridine.