220050-49-7Relevant academic research and scientific papers
Synthesis of 6-deoxyheptose derivatives via cyclic sulfates and oxetanes
Vargas-Berenguel, Antonio,Santoyo-Gonzalez, Francisco,Calvo-Asin, Jose A.,Calvo-Flores, Francisco G.,Exposito-Lopez, Juan M.,Hernandez-Mateo, Fernando,Isac-Garcia, Joaquin,Gimenez Martinez, Juan J.
, p. 1778 - 1786 (2007/10/03)
Two approaches for the chain elongation and synthesis of 6-deoxyheptose derivatives are described. The first one is based on the regioselective ring opening of 4,6-cyclic sulfate glycopyranoside derivatives at carbon 6 by cyanide ion. The second approach involves the ring expansion of 5,6-anhydro to 5,7-anhydro sugars and subsequent opening of the resulting oxetane, derivative using acetate ion as nucleophile.
