2201-42-5 Usage
Uses
Used in Pharmaceutical Research:
PCMP is used as a research chemical for studying the effects of NMDA receptor antagonists on the central nervous system. Its potent dissociative properties make it a valuable tool in understanding the mechanisms of action and potential therapeutic applications of similar compounds.
Used in Forensic Toxicology:
As a controlled substance, PCMP is used in forensic toxicology to identify and analyze its presence in biological samples, such as blood or urine, for legal and medical purposes. This helps in determining the cause of drug-related incidents and monitoring the prevalence of its use in the population.
Used in Drug Policy and Regulation:
PCMP is used as a case study in the development and implementation of drug policy and regulation. Its classification as a controlled substance and the associated legal and social implications provide insights into the challenges of managing the use and distribution of designer drugs and their potential impact on public health and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 2201-42-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,0 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 2201-42:
(6*2)+(5*2)+(4*0)+(3*1)+(2*4)+(1*2)=35
35 % 10 = 5
So 2201-42-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H27N.ClH/c1-16-10-14-19(15-11-16)18(12-6-3-7-13-18)17-8-4-2-5-9-17;/h2,4-5,8-9,16H,3,6-7,10-15H2,1H3;1H
2201-42-5Relevant academic research and scientific papers
Synthesis and preliminary biochemical evaluation of novel derivatives of PCP
Linders, Joannes T. M.,Furlano, David C.,Mattson, Mariena V.,Jacobson, Arthur E.,Rice, Kenner C.
scheme or table, p. 79 - 87 (2011/01/13)
(±)-Trans-Ph/Et and (±)-cis-Ph/Et 1-(2-ethyl-1- phenylcyclohexyl)piperidine were synthesized from 2-ethylcyclohexanone. In contrast to the corresponding trans-substituted 2-methyl compound which is 5x more potent than PCP, the trans-2-ethyl derivative has a 75x lower affinity for the PCP binding site. The cis-2-ethyl isomer is inactive like the cis-2-methyl derivative. (±)-1-(1-Phenylcyclohexyl)-2-methylpiperidine is almost as active as the parent PCP. Reduction of the aromatic ring or quaternization of the piperidine in PCP reduces the affinity for the PCP site.
