220108-44-1

Upstream product

• 50501-38-7 6-(hydroxymethyl)pyridine-2-carbonitrile 
• 74-88-4 methyl iodide 
• 10242-36-1 2-(hydroxymethyl)pyridine 1-oxide 
• 586-98-1 2-Hydroxymethylpyridine 

Downstream Products

• 220108-60-1 (4'R)-2-(3',4'-dihydro-4'-phenyl-2'-oxazolyl)-6-(methoxymethyl)pyridine 

Relevant academic research and scientific papers

Palladium-catalyzed allylic alkylation using pyridino-oxazolines and quinolino-oxazolines as ligands - Influence of steric factors

Four new chiral pyridino- and quinolino-oxazolines were subjected to the palladium-catalyzed alkylation of 1,3-diphenyl-2-propenyl acetate. The enantioselectivity varied (82-88% ee) with the steric properties of the ligands. The results are discussed in connection with results previously obtained using analogous ligands.