220167-99-7Relevant academic research and scientific papers
2-Methoxy-2-(1-naphthyl)propionic acid, a powerful chiral auxiliary for enantioresolution of alcohols and determination of their absolute configurations by the 1H NMR anisotropy method
Harada, Nobuyuki,Watanabe, Masataka,Kuwahara, Shunsuke,Sugio, Akinori,Kasai, Yusuke,Ichikawa, Akio
, p. 1249 - 1253 (2000)
Racemic 2-methoxy-2-(1-naphthyl)propionic acid (1, MαNP acid) was enantioresolved as its esters derived from various chiral alcohols. For example, a diastereomeric mixture of esters prepared from (±)-1 and (1R,3R,4S)-(-)-menthol was easily separated by HP
