220175-93-9Relevant academic research and scientific papers
High selective leishmanicidal activity of 3-hydroxy-2-methylene-3-(4-bromophenyl)propanenitrile and analogous compounds
de Souza,Pereira,Muzitano,Falcao,Rossi-Bergmann,Filho,Vasconcellos
, p. 99 - 102 (2007)
Sixteen not new aromatic compounds were prepared by one-pot reaction i.e. through Baylis-Hillman reaction and were the first time evaluated against promastigote Leishmania amazonensis and infected mammalian cells. Most of the compounds were selectively mo
Synthesis and biological evaluation of new epalrestat analogues as aldose reductase inhibitors (ARIs)
Reddy, Thatikonda Narendar,Ravinder, Mettu,Bagul, Pankaj,Ravikanti, Keerthi,Bagul, Chandrakant,Nanubolu, Jagadeesh Babu,Srinivas, Kolupula,Banerjee, Sanjay K.,Rao, Vaidya Jayathirtha
, p. 53 - 66 (2014/01/06)
Baylis-Hillman chemistry derived four series of new epalrestat analogues were synthesized. Three structural changes are introduced in these 39 new epalrestat analogues synthesized. All compounds were evaluated for their in vitro aldose reductase inhibitor
Synthesis of 1,3-Dialkyl-1,2,3-triazolium ionic liquids and their applications to the baylis-hillman reaction
Jeong, Yunkyung,Ryu, Jae-Sang
experimental part, p. 4183 - 4191 (2010/09/10)
Novel 1,3-dialkyl-1,2,3-triazolium ionic liquids were synthesized via click reactions using 1-trimethylsilylacetylene and alkyl azides and were efficient reaction media for the Baylis-Hillman reaction. The problems associated with deprotonation of the C-2
The Morita-Baylis-Hillman reaction in aqueous-organic solvent system
de Souza, Rodrigo O.M.A.,Pereira, Vera L.P.,Esteves, Pierre M.,Vasconcellos, Mario L.A. A.
scheme or table, p. 5902 - 5905 (2009/04/05)
We have found that water and organic solvents mixed at different proportions can give good to excellent yields and short reaction times for the Morita-Baylis-Hillman reaction. The present Letter details our findings in the Morita-Baylis-Hillman reaction b
