220184-54-3

Basic information

• Product Name: 2-(2-hydroxy-6-methylphenyl)amino-3-phenyl-propane-1-carbonitrile
• Synonyms: 2-(2-hydroxy-6-methylphenyl)amino-3-phenyl-propane-1-carbonitrile
• CAS NO: 220184-54-3
• Molecular Weight: 266.343
• Mol File: 220184-54-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2-hydroxy-6-methylphenyl)amino-3-phenyl-propane-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxy-6-methylphenyl)amino-3-phenyl-propane-1-carbonitrile(220184-54-3)
• EPA Substance Registry System: 2-(2-hydroxy-6-methylphenyl)amino-3-phenyl-propane-1-carbonitrile(220184-54-3)

Safety Data

• Hazardous Substances Data: 220184-54-3(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 74-90-8 hydrogen cyanide 
• 17672-22-9 2-amino-6-methylphenol 
• 2835-97-4 2-amino-3-methylphenol 
• 2179-92-2 tri-n-butyltin cyanide 

Downstream Products

• 262846-59-3 methyl 2-(2-methoxy-6-methylphenyl)amino-4-phenylbutanoate 

Relevant articles and documents

Optically active α-aminonitrile and process for producing α-amino acid

An aldehyde compound is reacted with an amino compound and hydrogen cyanate in the presence of a chiral zirconium catalyst obtained by mixing a zirconium alkoxide with an optically active binaphthol compound.

Catalytic, enantioselective synthesis of α-aminonitriles with a novel zirconium catalyst

Strecker reactions of aldimines with Bu3SnCN in the presence of the novel chiral zirconium binuclear catalyst 1 provide α-aminonitriles in good yields and with high enantioselectivities. The reaction can be applied to a wide range of substrates. Since both enantiomers of the choral sources are readily available, both enantiomers of the α-aminonitriles are easily prepared according to this method. L = N-methylimidazole.