220208-74-2

Basic information

• Product Name: N,N-diisopropyl-o-allyloxymethylbenzamide
• Synonyms: N,N-diisopropyl-o-allyloxymethylbenzamide
• CAS NO: 220208-74-2
• Molecular Weight: 275.391
• Mol File: 220208-74-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-diisopropyl-o-allyloxymethylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diisopropyl-o-allyloxymethylbenzamide(220208-74-2)
• EPA Substance Registry System: N,N-diisopropyl-o-allyloxymethylbenzamide(220208-74-2)

Safety Data

• Hazardous Substances Data: 220208-74-2(Hazardous Substances Data)

Upstream product

• 106-95-6 allyl bromide 
• 220208-72-0 2-(hydroxymethyl)-N,N-diisopropylbenzamide 
• 20383-28-2 N,N-diisopropyl benzamide 
• 103258-06-6 2-formyl-N,N-diisopropylbenzamide 

Relevant articles and documents

Sparteine-mediated enantioselective [2,3]-Wittig rearrangement of allyl ortho-substituted benzyl ethers and ortho-substituted benzyl prenyl ethers

The (-)-sparteine-mediated enantioselective [2,3]-Wittig rearrangement of N,N-dialkyl-o-allyloxymethylbenzamides and o-substituted benzyl prenyl ethers has been investigated. Enantiomeric excess up to 60% was observed as for the reaction with N,N-diethyl-o-allyloxymetylbenzamide. From the mechanistic investigations, it was suggested that the stereoinformation was introduced at the deprotonation step. Substoichiometric amount of (-)- sparteine (0.2 equiv.) did not decrease the enantioselectivity. Introduction of functional groups other than carbamoyl group did not enhance the enantioselectivity in this rearrangement.