220210-66-2Relevant academic research and scientific papers
Optimizing the synthesis of 5,10-disubstituted tripyrromethanes
Ka, Jae-Won,Lee, Chang-Hee
, p. 4609 - 4613 (2000)
Condensation of aldehydes with pyrrole in the presence of acid catalyst gave the mixture of dipyrromethanes and tripyrromethanes. The major product was switched from dipyrromethanes to tripyrromethanes according to the sequence of adding the reactants and
Microwave-assisted synthesis of non-substituted tripyrrane, tetrapyrrane and pentapyrrane
Saltsman, Irena,Gross, Zeev
, p. 247 - 249 (2008)
The microwave-assisted one-step condensation of aqueous formaldehyde with pyrrole was successfully applied for the preparation of non-substituted tri-, tetra- and pentapyrranes with reasonable yields. All three compounds are important precursors to advanced porphyrins and porphyrin analogs. The advantages of this method are short reaction times, clean reaction mixtures and work in the non-toxic and environment friendly solvent-water.
Corroles: The Hitherto Elusive Parent Macrocycle and its Metal Complexes
Fridman, Natalia,Gross, Zeev,Kumar, Amit,Kumar, Anil,Kumar, Sachin,Mahammed, Atif,Majdoub, Mahmoud,Saltsman, Irena,Yadav, Pinky
, p. 25097 - 25103 (2021)
Corroles, macrocycles that owe their name to the cobalt-chelating prosthetic group of vitamin B12 and share numerous features with the iron-chelating porphyrin present in heme proteins/enzymes, constantly cross new boundaries ever since stable derivatives became easily accessible. Particularly important is the increasing utilization of corroles and the corresponding metal complexes for the benefit of mankind, in terms of new drug candidates for treating various diseases and as catalysts for sustainable energy relevant processes. One challenge is to gain access to the plain macrocycle, as to allow for full elucidation of the most fundamental properties of corroles. We have obtained the substituent-free corrole by several surprising and conceptually different pathways. Selected features of the corresponding metal complexes are illuminated, for pointing towards unique phenomena that are anticipated to largely expand the horizon regarding their utilization for contemporary catalysis.
