220212-85-1Relevant academic research and scientific papers
Stereospecific displacement of 1-(pyridinyl)ethanols with amines and thiols via methanesulfonate esters; asymmetric synthesis of 1- (pyridinyl)ethylamines and sulfides
Uenishi, Jun'ichi,Takagi, Tomoko,Ueno, Tetsuya,Hiraoka, Takao,Yonemitsu, Osamu,Tsukube, Hiroshi
, p. 41 - 44 (1999)
Stereospecific reaction of optically pure (S)-1-(2-pyridinyl) ethanol methanesulfonate with aromatic and aliphatic amines, and thiols in DMSO gives (R)-1-(2-pyridinyl)ethylamine and sulfide with inversion of the configuration in good yields.
Stereospecific substitution of 1-(2-pyridinyl)-ethyl methanesulfonate with S- and O-nucleophiles
Uenishi, Jun'ichi,Hamada, Masahiro,Takagi, Tomoko,Yonemitsu, Osamu
, p. 735 - 746 (2007/10/03)
Nucleophilic substitution reactions of (S)- and (R)-1-(2-pyridinyl)ethyl methanesulfonate with S- and O-nucleophiles are described. The reaction of S-nucelophiles, such as aryl- and alkylthiols, and thioacetic acid, gave substituted sulfide and thioacetat
