220213-15-0 Usage
Description
4-(PIPERAZIN-1-YLMETHYL)BENZOIC ACID is an organic compound with the molecular formula C11H14N2O2. It is a white crystalline solid and serves as a key intermediate in the synthesis of various pharmaceutical compounds. Its structure features a benzoic acid core with a piperazine side chain attached to the 4-position, which contributes to its reactivity and potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
4-(PIPERAZIN-1-YLMETHYL)BENZOIC ACID is used as a reagent for the preparation of tetrahydrobenzothiophene carboxamides, which have similar functions as SCD1 inhibitors. SCD1 (Stearoyl-CoA Desaturase-1) is an enzyme involved in the regulation of lipid metabolism, and its inhibition can have potential therapeutic applications in treating metabolic disorders and obesity.
4-(PIPERAZIN-1-YLMETHYL)BENZOIC ACID is also used in the preparation of non-ATP competitive inhibitors of CDK2 (Cyclin-Dependent Kinase 2). CDK2 is a protein kinase that plays a crucial role in cell cycle regulation and is often overexpressed in various types of cancer. Inhibiting CDK2 activity can help in the development of anticancer drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 220213-15-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,2,1 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 220213-15:
(8*2)+(7*2)+(6*0)+(5*2)+(4*1)+(3*3)+(2*1)+(1*5)=60
60 % 10 = 0
So 220213-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O2/c15-12(16)11-3-1-10(2-4-11)9-14-7-5-13-6-8-14/h1-4,13H,5-9H2,(H,15,16)
220213-15-0Relevant articles and documents
Novel pyridopyrimidones and uses thereof
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, (2008/06/13)
This invention relates to compounds of the general formula: in which RA, RB and RC are as defined herein, and to their preparation and use.
Novel quinolinones and uses thereof
-
, (2008/06/13)
The invention relates to compounds of the general formula (and pharmaceutically acceptable derivatives thereof): 1in which RA, RB, RC, RD, R5, R7, R9, R9a, AK, p, q,
Novel pyridopyrimidines and uses thereof
-
, (2008/06/13)
This invention relates to compounds of the general formula: in which RA, RB, and RC are as defined herein, and to their preparation and use.
