220224-86-2 Usage
Uses
Used in Pharmaceutical Research:
(R,R)-1,2-Diphenyl-1,2-[di(pentafluorophenyl)phosphanoxy]ethane is used as a chiral ligand in pharmaceutical research for the synthesis of enantiomerically pure drugs. The ability of (R,R)-1,2-Diphenyl-1,2-[di(pentafluorophenyl)phosphanoxy]ethane to facilitate enantioselective transformations in metal-catalyzed reactions is crucial in producing the desired chiral molecules with high selectivity, which is essential for the development of effective and safe medications.
Used in Organic Synthesis:
In the field of organic synthesis, (R,R)-1,2-Diphenyl-1,2-[di(pentafluorophenyl)phosphanoxy]ethane is utilized as a versatile ligand for various catalytic applications. Its steric properties and selective reactivity enable the synthesis of complex organic molecules with high precision, making it an indispensable tool for creating novel compounds with potential applications in various industries.
Used in Asymmetric Catalysis:
(R,R)-1,2-Diphenyl-1,2-[di(pentafluorophenyl)phosphanoxy]ethane is employed as a key component in asymmetric catalysis, a sub-discipline of organometallic chemistry. It is used as a ligand to enhance the enantioselectivity of metal catalysts, which is vital for producing chiral compounds with specific spatial arrangements. This application is particularly relevant in the synthesis of biologically active molecules and pharmaceuticals, where the stereochemistry of the molecule can significantly impact its efficacy and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 220224-86-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,2,2 and 4 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 220224-86:
(8*2)+(7*2)+(6*0)+(5*2)+(4*2)+(3*4)+(2*8)+(1*6)=82
82 % 10 = 2
So 220224-86-2 is a valid CAS Registry Number.
220224-86-2Relevant academic research and scientific papers
A new chiral ligand for the Fe-Lewis acid catalysed asymmetric Diels-Alder reaction
Bruin, Marion E.,Peter Kuendig
, p. 2635 - 2636 (2007/10/03)
The readily accessible enantiopure hydrobenzoin forms the backbone of the new bidentate ligand BIPHOP-F that is shown here to provide the chiral environment for a highly enantioselective Fe-Lewis acid catalysed Diels-Alder reaction between α,β-enals and dienes.
