220256-94-0

Basic information

• Product Name: 1,3-Dioxan-5-ol, 2-(4-methoxyphenyl)-4-(2-propenyl)-, (2R,4S,5R)-
• CAS NO: 220256-94-0
• Molecular Formula: C14H18O4
• Molecular Weight: 250.295
• Mol File: 220256-94-0.mol

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxan-5-ol, 2-(4-methoxyphenyl)-4-(2-propenyl)-, (2R,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxan-5-ol, 2-(4-methoxyphenyl)-4-(2-propenyl)-, (2R,4S,5R)-(220256-94-0)
• EPA Substance Registry System: 1,3-Dioxan-5-ol, 2-(4-methoxyphenyl)-4-(2-propenyl)-, (2R,4S,5R)-(220256-94-0)

Safety Data

• Hazardous Substances Data: 220256-94-0(Hazardous Substances Data)

Upstream product

• 79364-36-6 (2R,3S)-hex-5-ene-1,2,3-triol 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 

Downstream Products

• 337309-17-8 [(2R,4S,5R)-4-Allyl-2-(4-methoxy-phenyl)-[1,3]dioxan-5-yloxy]-acetic acid tert-butyl ester 
• 1186291-32-6 C₁₅H₂₀O₄ 
• 440117-05-5 (2R,4S,5R)-4-allyl-5-[(3-tert-butyldiphenylsilyloxy)prop-1-ynyloxy]-2-(4-methoxyphenyl)-1,3-dioxane 
• 440117-03-3 (2R,4S,5R)-4-allyl-5-[(3-acetoxy)prop-1-ynyloxy]-2-(4-methoxyphenyl)-1,3-dioxane 
• 440117-01-1 (2R,4S,5R)-4-allyl-2-(4-methoxyphenyl)-5-[(3-hydroxy)prop-1-ynyloxy]-1,3-dioxane 

Relevant articles and documents

Convergent synthesis of the HIJKLM ring fragment of ciguatoxin CTX3C

Ciguatoxin CTX3C is a representative congener of the ciguatoxins, which are known to be the principal causative agents of ciguatera food poisoning. The structure of CTX3C spans more than 3nm and is characterized by 13 ether rings. To attain a practical construction of this molecule, efficient supplies of the structural fragments are crucial. Herein we report the convergent synthesis of the HIJKLM ring fragment and present a new carbonyl olefination protocol to cyclize the J ring using low-valent titanium.

Formal total synthesis of ascidiatrienolide A and the didemnilactones

A concise synthesis of the ten-membered lactone 26 is described which constitutes the key intermediate of a previous total synthesis of the marine natural product ascidiatrienolide 1 and can also be elaborated into the closely related didemnilactones 2-4.