220273-37-0

Upstream product

• 626-19-7 Isophthalaldehyde 
• 153277-56-6 C₁₃H₂₅NOSSi₂ 
• 188447-91-8 (S)-p-toluenesulfinimide 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 

Downstream Products

• 220273-59-6 (S)-3-{3-[(R)-2-Methoxycarbonyl-1-((S)-toluene-4-sulfinylamino)-ethyl]-phenyl}-3-((S)-toluene-4-sulfinylamino)-propionic acid methyl ester 
• 220273-45-0 (R)-3-{3-[(R)-2-Methoxycarbonyl-1-((S)-toluene-4-sulfinylamino)-ethyl]-phenyl}-3-((S)-toluene-4-sulfinylamino)-propionic acid methyl ester 
• 1253851-79-4 (S,S)-1,3-bis-(p-tolylsulfinamidemethyl)benzene 

Relevant academic research and scientific papers

Chiral sulfur derivatives in the allylation of acyl hydrazones: C 2-symmetric bis-sulfinamides as enhanced chiral organic promoters.

Monosulfinamides and C2-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl hydrazones, the nature of the spacer and the substituent at the sulfinyl sulfur are key elements for the enantioselectivity of the process.

A stereoselective synthesis of bis-β-amino acids

Enantiopure bis-β-amino acids (5a-c) were prepared from chiral bis- sulfinimines (3a-c) in >97% ee via stereoselective addition of the sodium enolate of methyl acetate followed by hydrolysis.