220280-47-7 Usage
Uses
Used in Pharmaceutical Research:
2,4-Pyrrolidinedimethanol,3-amino, (2S,3S,4S)-(9CI) is used as a chiral building block in pharmaceutical research for the development of pharmaceutical drugs. Its unique stereochemistry allows for the creation of enantiomerically pure compounds, which is crucial for ensuring the desired biological activity and minimizing potential side effects.
Used in Organic Synthesis:
In the field of organic synthesis, 2,4-Pyrrolidinedimethanol,3-amino, (2S,3S,4S)-(9CI) serves as a versatile chiral building block. Its pyrrolidine ring and functional groups can be further modified and incorporated into more complex molecules, enabling the synthesis of a wide range of chiral compounds with potential applications in various industries.
Used in Chiral Separation Techniques:
2,4-Pyrrolidinedimethanol,3-amino, (2S,3S,4S)-(9CI) can be employed in chiral separation techniques, such as chromatography and crystallization, to resolve enantiomers and obtain pure enantiomeric forms of other chiral compounds. This is particularly important in the pharmaceutical industry, where the desired enantiomer often exhibits the desired therapeutic effect, while the other enantiomer may be inactive or even harmful.
Used in Drug Development:
In drug development, 2,4-Pyrrolidinedimethanol,3-amino, (2S,3S,4S)-(9CI) can be utilized as a key intermediate in the synthesis of chiral drugs. Its unique structure and stereochemistry can be exploited to design and synthesize novel pharmaceutical compounds with improved efficacy, selectivity, and reduced side effects.
Used in Chemical Industry:
Beyond pharmaceutical applications, 2,4-Pyrrolidinedimethanol,3-amino, (2S,3S,4S)-(9CI) also has potential uses in the chemical industry. Its chiral properties and functional groups can be employed in the synthesis of various chiral chemicals, such as chiral solvents, chiral catalysts, and chiral ligands, which are essential for enantioselective reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 220280-47-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,2,8 and 0 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 220280-47:
(8*2)+(7*2)+(6*0)+(5*2)+(4*8)+(3*0)+(2*4)+(1*7)=87
87 % 10 = 7
So 220280-47-7 is a valid CAS Registry Number.
220280-47-7Relevant academic research and scientific papers
IOOC route to substituted chiral pyrrolidines. Potential glycosidase inhibitors
Falb, Eliezer,Bechor, Yosi,Nudelman, Abraham,Hassner, Alfred,Albeck, Amnon,Gottlieb, Hugo E.
, p. 498 - 506 (2007/10/03)
Branched-chain five-membered ring aza-sugar analogues, synthesized from amino acids by an intramolecular oxime-olefin cycloaddition reaction, the IOOC route, were found to be selective glycosidase inhibitors. The derivative 2,4(S)-di(hydroxymethyl)-3(S)-aminopyrrolidine, obtained from D-serine, was about 1 order of potency more active than its enantiomer obtained from L- serine.
Utilization of L-serine in an oxime olefin cycloaddition route to a functionalized asymmetric pyrrolidine, a selective α-glucosidase inhibitor
Hassner, Alfred,Falb, Eliezer,Nudelman, Abraham,Albeck, Amnon,Gottlieb, Hugo E.
, p. 2397 - 2400 (2007/10/02)
A new route for asymmetric aza-sugar analogs starting with L-serine and utilizing an intramolecular oxime olefin cycloaddition has been successfully developed. A member of this family of branched chain sugar amino di(hydroxymethyl) pyrrolidines (1 and 2) exhibits selective inhibition of α-glucosidase, while no inhibition of β-glucosidase was detected.
