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20-Hydroxyecdysone 25-acetate, also known as viticosterone E, is a derivative of 20-hydroxyecdysone (20E) where an acetate group is selectively conjugated at the 25-position. This modification enhances its potential for applications in prolonged-action pharmaceuticals, as demonstrated by its synthesis and use in creating further derivatives such as melandrioside A, a galactoside of viticosterone E. Its selective esterification at the 25-position highlights its utility in developing bioactive compounds with tailored properties.

22033-96-1

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22033-96-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 22033-96-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,0,3 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 22033-96:
(7*2)+(6*2)+(5*0)+(4*3)+(3*3)+(2*9)+(1*6)=71
71 % 10 = 1
So 22033-96-1 is a valid CAS Registry Number.

22033-96-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name viticosterone E

1.2 Other means of identification

Product number -
Other names Acetic acid (4S,5R)-4,5-dihydroxy-1,1-dimethyl-5-((2S,3R,5R,9R,10R,13R,14S)-2,3,14-trihydroxy-10,13-dimethyl-6-oxo-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-hexyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22033-96-1 SDS

22033-96-1Downstream Products

22033-96-1Relevant academic research and scientific papers

New derivatives of 20-hydroxyecdyzone. Viticosterone E synthesis

Galyautdinov,Nazmeeva,Savchenko,Ves'Kina,Nedopekin,Fatykhov,Khalilov,Odinokov

, p. 675 - 684 (2004)

New 20,22-mono- and 2,3:20,22-diacetals of 20-hydroxyecdyzone were synthesized, and some thereof were applied to the synthesis of 25-O-acetyl-20-hydroxyecdyzone (viticosterone E).

Synthesis of 20-hydroxyecdysone 25-acetate

Politova,Punegov,Volodin,Ignatov

, p. 57 - 60 (1997)

A scheme has been developed for the selective conjugation of 20-hydroxyecdysone (20E) at the 25-position, with the synthesis of 20E 25-acetate as an example. The proposed scheme also permits the selective synthesis of 20E 22-esters from both lower and higher fatty acids, which opens up prospects for the creation from them of drugs with a prolonged action.

PHYTOECDYSTEROIDS OF PLANTS OF THE GENUS Melandrium II. MELANDRIOSIDE A - A GALACTOSIDE OF VITICOSTERONE E FROM Melandrium turkestanicum

Saatov, Z.,Gorovits, M. B.,Abubakirov, N. K.

, p. 449 - 451 (1991)

The isolation and determination of the structure of the new phytoecdysteroid melandroside A are described; it is viticosterone E 22-O-α-D-galactopyranoside.

Selective Acetylation of 20-Hydroxyecdysone. Partial Synthesis of Some Minor Ecdysteroids and Analogues

Suksamrarn, Apichart,Pattanaprateep, Prasert

, p. 10633 - 10650 (2007/10/02)

Selective acetylation of the 2,3- and 20,22-acetonide and 2,3:20,22-diacetonide derivatives of 20-hydroxyecdysone and subsequent removal of the protecting groups led to partial synthesis of a number of mono-, di- and triacetate derivatives of 20-hydroxyecdysone.Some of these acetate derivatives are minor, naturally occurring ecdysteroids.

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