220352-11-4

Basic information

• Product Name: (R)-dihydro-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2(3H)-furanone
• Synonyms: (R)-dihydro-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2(3H)-furanone
• CAS NO: 220352-11-4
• Molecular Weight: 340.494
• Mol File: 220352-11-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (R)-dihydro-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2(3H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-dihydro-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2(3H)-furanone(220352-11-4)
• EPA Substance Registry System: (R)-dihydro-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2(3H)-furanone(220352-11-4)

Safety Data

• Hazardous Substances Data: 220352-11-4(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 19444-84-9 3-deoxy-L-glycero-tetronolactone 

Downstream Products

• 1134117-49-9 (R)-2-(tert-butyldiphenylsilyloxy)-4-hydroxy-N-(5-(N-thiazol-2-ylsulfamoyl)pyridine-2-yl)butanamide 
• 1203587-17-0 (R)-2-(tert-butyldiphenylsilyloxy)-4-hydroxy-N-phenylbutanamide 
• 943654-01-1 (R)-2-(tert-butyldiphenylsilyloxy)-4-hydroxy-N-(4-(N-thiazol-2-ylsulfamoyl)phenyl)butanamide 

Relevant articles and documents

HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS

The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

Epothilon derivatives, method for the production and the use thereof as pharmaceuticals

Disclosed are epothilone compounds of formula I, which are useful as pharmaceutical compounds for treating, for example, malignant tumors and chronic inflammatory diseases and are useful in anti-angiogenesis therapy.