220446-65-1

Upstream product

• 220446-51-5 (E)-5-phenyl-1-pentene-1-one O-pentafluorobenzoyloxime 
• 220446-53-7 1-phenyl-4-penten-1-one (Z)-O-pentafluorobenzoyloxime 
• 59239-04-2 (E)-1-phenylpent-4-en-1-one oxime 
• 152957-08-9 (Z)-1-phenylpent-4-en-1-one oxime 

Downstream Products

• 3042-21-5 2-methyl-5-phenyl-1H-pyrrole 

Relevant academic research and scientific papers

Synthesis of pyrrole derivatives by palladium-catalyzed cyclization of γ,δ-unsaturated ketone o-pentafluorobenzoyloximes

Various pyrrole derivatives are synthesized from γ,δ-unsaturated ketone O-pentafluorobenzoyloximes by treatment with catalytic amounts of Pd(PPh3)4 and triethylamine via alkylideneaminopalladium(II) intermediates generated by oxidative addition of the oximes to the Pd(0) complex.

Synthesis of pyrrole derivatives by the heck-type cyclization of γ,δ-unsaturated ketone O-pentafluorobenzoyloximes

Substituted pyrroles are synthesized from γδ-unsaturated ketone O-pentafluorobenzoyloximes by the intramolecular Heck-type amination of the olefinic moiety catalyzed by Pd(PPh3)4.