220510-03-2 Usage
Description
5-(Morpholin-4-ylsulfonyl)-1H-indole-2,3-dione is a chemical compound characterized by its molecular formula C12H11N1O5S1. It is a white to off-white powder with a molecular weight of 285.29 g/mol. 5-(MORPHOLIN-4-YLSULFONYL)-1H-INDOLE-2,3-DIONE is known for its potential biological activities, such as antitumor and antiproliferative properties, and is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various organic compounds. It has garnered interest among researchers and scientists in the field of medicinal chemistry and drug discovery due to its potential use in developing novel drugs for the treatment of various diseases.
Uses
Used in Pharmaceutical Industry:
5-(Morpholin-4-ylsulfonyl)-1H-indole-2,3-dione is used as an intermediate in the synthesis of various organic compounds for pharmaceutical applications. Its potential biological activities, such as antitumor and antiproliferative properties, make it a valuable compound for the development of novel drugs to treat a range of diseases.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 5-(Morpholin-4-ylsulfonyl)-1H-indole-2,3-dione is utilized for its potential biological activities. Researchers and scientists are investigating its antitumor and antiproliferative properties to explore its potential use in creating new therapeutic agents for various diseases.
Used in Drug Discovery:
5-(Morpholin-4-ylsulfonyl)-1H-indole-2,3-dione is a compound of interest in drug discovery due to its potential to contribute to the development of novel drugs. Its unique properties and applications in the pharmaceutical industry make it a promising candidate for further research and development to address unmet medical needs.
Check Digit Verification of cas no
The CAS Registry Mumber 220510-03-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,5,1 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 220510-03:
(8*2)+(7*2)+(6*0)+(5*5)+(4*1)+(3*0)+(2*0)+(1*3)=62
62 % 10 = 2
So 220510-03-2 is a valid CAS Registry Number.
220510-03-2Relevant articles and documents
Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3, 4-c]quinoline-1,3-diones
Kravchenko, Dmitri V.,Kysil, Volodymyr M.,Tkachenko, Sergey E.,Maliarchouk, Sergey,Okun, Ilya M.,Ivachtchenko, Alexandre V.
, p. 1377 - 1383 (2005)
Synthesis, biological evaluation and structure-activity relationships for a series of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-1,3-dioxo-2,3- dihydro-1H-pyrrolo[3,4-c]quinolines are described. These compounds represent a new chemotype of nonpeptid
SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT
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Page/Page column 121, (2010/08/04)
Provided are 3-substituted oxindole derivatives which are agonists of the CB2 receptor, pharmaceutical compositions containing the same, and methods of treatment related to CB2-mediated disorders (e.g., pain, cancer etc.) using the 3-substituted oxindole derivatives and compositions described herein.
INHIBITION OF SHP2/PTPN11 PROTEIN TYROSINE PHOSPHATASE BY NSC-87877, NSC-117199 AND THEIR ANALOGS
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Page/Page column 33, (2010/11/28)
Compounds and associated methods for inhibiting a protein tyrosine phosphatase. By a combination of experimental and virtual screenings of the NCI Diversity Set chemical library, NSC-87877 and NSC-117199 have been identified as Shp2 PTP inhibitors. Signif
