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L-Tyrosine, N-[[(4R)-5,5-dimethyl-3-[(1-methyl-1H-pyrazol-4-yl)sulfonyl]-4-thiazolidin yl]carbonyl]-, dimethylcarbamate (ester) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

220545-25-5

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220545-25-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 220545-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,5,4 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 220545-25:
(8*2)+(7*2)+(6*0)+(5*5)+(4*4)+(3*5)+(2*2)+(1*5)=95
95 % 10 = 5
So 220545-25-5 is a valid CAS Registry Number.

220545-25-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(1-methylpyrazole-4-sulfonyl)-L-(5,5-dimethyl)thiaprolyl-L-4-(N,N-dimethylcarbamyloxy)phenylalanine

1.2 Other means of identification

Product number -
Other names (S)-3-(4-Dimethylcarbamoyloxy-phenyl)-2-{[(R)-5,5-dimethyl-3-(1-methyl-1H-pyrazole-4-sulfonyl)-thiazolidine-4-carbonyl]-amino}-propionic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:220545-25-5 SDS

220545-25-5Downstream Products

220545-25-5Relevant academic research and scientific papers

STEROID SPARING AGENTS AND METHODS OF USING SAME

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Page/Page column 432-433, (2010/02/14)

This invention relates generally to the use of a steroid sparing agent for the preparation of a medicament for the treatment of inflammatory bowel diseases (IBD), asthma, multiple sclerosis (MS), rheumatoid arthritis (RA), graft versus host disease (GVHD), host versus graft disease, and various spondyloarthropathies, comprising administering a steroid sparing immunoglobulin or small molecule composition to a patient in need thereof. The invention also relates generally to combination therapies for the treatment of these conditions.

Synthesis, characterization and evaluation of pro-drugs of VLA-4 antagonists

Huryn, Donna M.,Ashwell, Susan,Baudy, Reinhardt,Dressen, Darren B.,Gallaway, William,Grant, Francine S.,Konradi, Andrei,Ley, Robert W.,Petusky, Susan,Pleiss, Michael A.,Sarantakis, Dimitri,Semko, Christopher M.,Sherman, Mary M.,Tio, Cesar,Zhang, Lu

, p. 1651 - 1654 (2007/10/03)

A pro-drug strategy to identify orally efficacious VLA-4 antagonists is described. Potential pro-drugs were evaluated for their physical chemical characteristics and in vitro properties, including solubility, stability, permeability and plasma stability.

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