220574-31-2

Upstream product

• 65317-09-1 2-propenyltrichlorostannane 
• 153463-32-2 (S)-4-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(4-methoxyphenyl)azetidine-2,3-dione 
• 106-95-6 allyl bromide 
• 762-72-1 allyl-trimethyl-silane 
• 103174-02-3 (3R,4S)-cis-1-(p-anisyl)-3-acetoxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 141781-24-0 [1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-meth-(E)-ylidene]-(4-methoxy-phenyl)-amine 
• 115828-87-0 (3R,4S)-cis-1-(p-anisyl)-3-hydroxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 24850-33-7 allyltributylstanane 

Downstream Products

• 761457-12-9 (3S,4R)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-(4-methoxy-phenyl)-5-oxa-2-aza-spiro[3.5]non-7-en-1-one 
• 1002327-67-4 C₂₁H₂₅NO₆ 
• 1002327-69-6 C₂₁H₂₅NO₅ 
• 1002327-66-3 C₂₂H₂₇NO₇ 

Relevant academic research and scientific papers

Asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-β-lactams via novel, highly stereoselective Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones

New asymmetric routes based on both Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones are used for the highly stereoselective, efficient preparation of densely functionalized 3-substituted 3-hydroxy-β-lactams.

Metal-assisted synthesis of enantiopure spirocyclic β-lactams from azetidine-2,3-diones

A novel approach to enantiopure spirocyclic β-lactams has been developed by using different intramolecular metal-catalyzed cyclization reactions in monocyclic unsaturated alcohols. A novel approach to enantiopure spirocyclic β-lactams has been developed b

Diversity-oriented preparation of enantiopure spirocyclic 2-azetidinones from α-oxo-β-lactams through barbier-type reactions followed by metal-catalyzed cyclizations

Novel, simple, and convenient strategies to diversely functionalized spirocyclic β-lactams have been developed by using different metal-mediated carbonyl addition/cyclization reaction sequences. Spirocyclization precursors, 2-azetidinone-tethered homoally

N1-C4 β-lactam bond cleavage in the 2-(trimethylsilyl)thiazole addition to β-lactam aldehydes: Asymmetric synthesis of spiranic and tertiary α-alkoxy-γ-keto acid derivatives

Starting substrates, enantiopure spiranic or 3-substituted 3-alkoxy-4-oxoazetidine-2-carbaldehydes, were prepared from (R)-2,3-O- isopropylideneglyceraldehyde derived azetidine-2,3-diones by sequential Barbier-type addition reactions followed by hydroxy f

New aspects of the indium chemistry of carbonyl-β-lactams

Reactions of racemic as well as optically pure carbonyl-β-lactams with stabilized organo-indium reagents were investigated in aqueous media. The regio- and stereochemistry of the processes were generally good, offering a convenient asymmetric entry to den

Metal-promoted allylation, propargylation, or allenylation of azetidine-2,3-diones in aqueous and anhydrous media. Application to the asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-β-lactams

Metal-mediated carbonyl allylation, allenylation, and propargylation of optically pure azetidine-2,3-diones were investigated in both anhydrous and aqueous environments. Different metals promoters showed varied regioselectivities on product formation duri