220583-65-3Relevant academic research and scientific papers
Anti-aldol reactions of lactate-derived ketones. Application to the synthesis of (-)-tetrahydrolipstatin
Paterson,Doughty
, p. 393 - 394 (1999)
(-)-Tetrahydrolipstatin (1) was prepared with a high level of stereocontrol (>98% ds) by employing a boron-mediated, anti-selective, aldol coupling between the (R)-lactate-derived ketone 7 and the aldehyde 8.
