220628-98-8

Upstream product

• 100517-41-7 quinoline-8-carbonyl chloride 
• 72-18-4 L-valine 
• 86-59-9 8-carboxyquinoline 
• 220628-88-6 (S)-N-<2-hydroxy-1-(1-methylethyl)ethyl>-8-quinolinecarboxamide 
• 2026-48-4 (S)-valinol 
• 40245-26-9 quinoline-8-carboxylic acid methyl ester 
• 220628-93-3 (1'S)-N-(1'-isopropyl-2'-chloroethyl)-8-quinolinecarboxamide 

Relevant academic research and scientific papers

Chiral pyridylmethyl- and quinolinyl-oxazolines as ligands for enantioselective palladium-catalyzed allylic alkylation

Chiral pyridylmethyl- and quinolinyl-oxazolines were prepared and assessed in the enantioselective palladium-catalyzed allylic substitution of 1,3-diphenylprop-2-enyl acetate with dimethyl malonate. Enantioselectivities up to 77% were obtained.

Chiral quinolinyl-oxazolines as ligands for copper(I)-catalyzed asymmetric cyclopropanation

Chiral quinolinyl-oxazoline compounds have been synthesized from enantiomerically pure amino alcohols and 8-quinoline-carboxylic acid using a convenient procedure. Asymmetric cyccopropanation of styrene with diazoacetates in the presence of 1 mol% of CuOTf and quinolinyl-oxazolines gave 2-phenylcyclopropane carboxylates in moderate enantiomeric excesses.