220658-18-4Relevant academic research and scientific papers
Cu(I) catalysed cyclopropanation of olefins: Stereoselectivity studies with Arylid-Box and Isbut-Box ligands
Burke, Anthony J.,Palma Carreiro, Elisabete da,Chercheja, Serghei,Moura, Nuno M.M.,Prates Ramalho,Rodrigues, Ana Isabel,dos Santos, Carla I.M.
, p. 4863 - 4874 (2007)
In our quest to find new ligands for highly stereoselective reactions, we tested a variety of chiral non-racemic pseudo-C2 symmetric bis-oxazolines derived from malonic acid containing an arylidene bridge unit (and appropriately termed Arylid-B
Synthesis, characterization and antimicrobial activity of novel pharmacophores incorporating imidazoline-oxazoline scaffold
Barakat, Assem,Al-Majid, Abdullah Mohammed,Al-Qahatany, Faisal M.,Islam, Mohammad Shahidul,Al-Agamy, Mohamed H.M.
, p. 562 - 568 (2014/03/21)
In this work, synthesis, characterization and antimicrobial activity of series of imidazolines-oxazolines scaffolds 5a-f and 10a-d have been investigated. All the imidazolines-oxazolines derivatives were prepared from acid derivatives 1 and 6a-c, and enan
Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis
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Page 3; sheet 22, (2010/02/03)
The subject invention provides pharmaceutical compounds useful in the treatment of Type II diabetes. These compounds are advantageous because they are readily metabolized by the metabolic drug detoxification systems. Particularly, thiazolidinedione analogs that have been designed to include esters within the structure of the compounds are provided. This invention is also drawn to methods of treating disorders, such as diabetes, comprising the administration of therapeutically effective compositions comprising compounds that have been designed to be metabolized by serum or intracellular hydrolases and esterases. Pharmaceutical compositions of the ester-containing thiazolidinedione analogs are also taught.
